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diazepam will raise the level or influence of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. stay Valium 10mg till salu clear of or Use Alternate Drug. If coadministration of lonafarnib (a sensitive CYP3A substrate) with weak CYP3A inhibitors is unavoidable, lessen to, or continue on lonafarnib at starting off dose. I de fles